Sugiyama Laboratory

Kozue Okamura

Doctor student, 2nd year

Room: 5C04

Mail: k-okamura(at)pse.t.u-tokyo.ac.jp (Replace (at) with @.)

Tel: 26876 (Add the last 4 digits to +81-3-5841.)

Short C.V.

2021–

2021- Student of a special grant "Leadership Development Program for Ph.D." from Graduate School of Engineering, the University of Tokyo

2021–

Student of World-leading Innovative Graduate Study Program on Global Leadership for Social Design and Management (WINGS-GSDM)

2021–

PhD candidate, The University of Tokyo

2019–2021

Student of Global Leader Program for Social Design and Management (GSDM)

2019–2021

Master of Engineering in Chemical System Engineering, The University of Tokyo

2015–2019

Bachelor of Engineering in Chemical System Engineering, The University of Tokyo

Research

Aiming at developing a tool to support process design efforts for the production of monoclonal antibodies (mAb)s. The tool incorporates:
・ Modeling cell cultivation using hybrid models
・ Evaluating the cultivation process in terms of productivity and product quality
・ Developing a framework towards the selection of preferable cultivation modes

Publication

Eri Amasawa, Hiroaki Kuroda, Kozue Okamura, Sara Badr, and Hirokazu Sugiyama, "Cost–Benefit Analysis of Monoclonal Antibody Cultivation Scenarios in Terms of Life Cycle Environmental Impact and Operating Cost" ACS Sustainable Chemistry & Engineering, 9, 14012–14021 (2021)
DOI: 10.1021/acssuschemeng.1c01435

Junu Kim, Kensaku Matsunami, Kozue Okamura, Sara Badr, Hirokazu Sugiyama, "Determination of critical decision points for COVID-19 measures in Japan" Scientific Reports, 11, 16416 (2021)
DOI: 10.1038/s41598-021-95617-z

Sara Badr, Kozue Okamura, Nozomi Takahashi, Vera Ubbenjans, Haruku Shirahata, Hirokazu Sugiyama, "Integrated Design of Biopharmaceutical Manufacturing Processes: Operation Modes and Process Configurations for Monoclonal Antibody Production" Computers and Chemical Engineering, 153, 107422 (2021)
DOI: 10.1016/j.compchemeng.2021.107422

Conferences (as a presenter)

Kozue Okamura, Sara Badr, Sei Murakami, Hirokazu Sugiyama "Hybrid modelling of CHO-MK cell cultivation in monoclonal antibody production", Oral, The 14th International Symposium on Process Systems Engineering (PSE 2021+), 19–23 June 2022, Kyoto University Clock Tower Centennial Hall, Kyoto, Japan/Virtual meeting

Kozue Okamura*, Rio Hamada, Hiroki Tsuchiya, Seiichi Ohta, Hirokzau Sugiyama "Cost-effectiveness modelling and analysis of companion diagnostics" Oral, Society of Chemical Engineers, Japan (SCEJ) 87th Annual Meeting, 16-18 March 2022, Tsurukabuto Campus, Kobe University, Kobe city, Hyogo/Virtual meeting

Kozue Okamura*, Sara Badr, Hirokazu Sugiyama "Hybrid modeling of cell cultivation towards integrated design of monoclonal antibody production processes" Poster, Society of Chemical Engineers, Japan (SCEJ) 86th Annual Meeting, 20-22 March 2021, Virtual meeting Student Award (Poster)

Kozue Okamura*, Sara Badr, Hirokazu Sugiyama "Simulation of cultivation processes in monoclonal antibody production towards the selection of operation modes" Oral, The 9th Asian Symposium on Process Systems Engineering (9th PSE Asia), 4–6 November 2020, Virtual meeting

Kozue Okamura*, Sara Badr, Hirokazu Sugiyama "Process simulation for the decision making on cell cultivation modes in monoclonal antibody production", Abstract, Society of Chemical Engineers, Japan (SCEJ) 85th Annual Meeting

Kozue Okamura*, Sara Badr, Hirokazu Sugiyama "Dynamic simulation and process assessment of cultivation modes in monoclonal antibody production using pilot-scale experimental data", Oral, 2019 AIChE Annual Meeting, 10–15 November 2019, Hyatt Regency, Orlando, U.S.A.

Kozue Okamura* "Continuous manufacturing of biopharmaceuticals" Oral, ISPE Japan Affiliate Annual Meeting 2019, 30–31 May 2019, Tower Hall Funabori, Tokyo, Japan

Kozue Okamura*, Sara Badr, Hirokazu Sugiyama "Dynamic simulation and process assessment of cell cultivation modes in monoclonal antibody production" Poster, SCEJ 84th Annual Meeting, 13–15 March 2019, Shibaura Institute of Technology, Tokyo, Japan Student Award (Poster)

Conferences (as a co-author)

Sara Badr, Kozue Okamura, Nozomi Takahashi, Hirokazu Sugiyama "Techno-economic assessment of upstream and downstream process alternatives for the production of monoclonal antibodies", Oral, The 14th International Symposium on Process Systems Engineering (PSE 2021+), 19–23 June 2022, Kyoto University Clock Tower Centennial Hall, Kyoto, Japan/Virtual meeting

Eri Amasawa*, Hiroaki Kuroda, Kozue Okamura, Sara Badr, Hirokazu Sugiyama "Holistic assessment of monoclonal antibody production" Oral, The 17th Meeting of the Institute of Life Cycle Assessment, 2-4 March 2022, Online

Kensaku Matsunami*, Junu Kim, Kozue Okamura, Yusuke Ichida, Shungo Matsueda, Sara Badr, Hirokazu Sugiyama "Mathematical models for infectious diseases considering the impacts of mobility, therapeutic agents, and vaccines" Oral, Society of Chemical Engineers, Japan (SCEJ) 52nd Autumn Meeting, September 2021, Tsushima Campus, Okayama University, Okayama city, Okayama/Virtual meeting

Max Berthet*, Kozue Okamura, Yang Li, Saeko Kawataki, Paul Nadeau "Student-Led Design of Online Tools to Support the Quality of Research Life at the University of Tokyo: A Survey-Based Approach" Oral, 9th European Conference on Education, 15-18 July 2021, Online

Badr Sara*, Okamura Kozue, Takahashi Nozomi, Sugiyama Hirokazu "Assessment of robustness and operational considerations for the design of integrated mAb manufacturing processes" Oral, Society of Chemical Engineers, Japan (SCEJ) 86th Annual Meeting, 20-22 March 2021, Virtual meeting

Sara Badr*, Kozue Okamura, Nozomi Takahashi, Hirokazu Sugiyama "Design of Integrated Monoclonal Antibody Production Processes: Modelling, Data, and Process Challenges" Oral, 2020 AIChE Annual Meeting, 16–20 November 2020, Virtual meeting

Sara Badr*, Kozue Okamura, Nozomi Takahashi, Vera Ubbenjans, Haruku Shirahata, Hirokazu Sugiyama "Integrated design of biopharmaceutical manufacturing processes: operation modes and process configurations for monoclonal antibody production" Oral, The 30th European Symposium on Computer-Aided Process Engineering (ESCAPE-30), 30 August–2 September 2020, Virtual meeting

Max Berthet*, Saeko Kawataki, Kozue Okamura, Mizuki Ishida, Karthik Varada "Understanding and Promoting Gender Diversity Among Senior Faculty at the University of Tokyo: A Student Action Project" Oral, 10th Asian Conference on Cultural Studies, 27–30 May 2020, Online

Proceedings

Kozue Okamura, Sara Badr, Sei Murakami, Hirokazu Sugiyama "Hybrid modelling of CHO-MK cell cultivation in monoclonal antibody production" 14th International Symposium on Process System Engineering, Elsevier, Computer Aided Chemical Engineering, 49, 2137–2142 (2022)

Sara Badr, Kozue Okamura, Nozomi Takahashi, Hirokazu Sugiyama "Techno-economic assessment of upstream and downstream process alternatives for the production of monoclonal antibodies" 14th International Symposium on Process System Engineering, Elsevier, Computer Aided Chemical Engineering, 49, 745–750 (2022)

Sara Badr, Kozue Okamura, Nozomi Takahashi, Vera Ubbenjans, Haruku Shirahata, Hirokazu Sugiyama "Integrated design of biopharmaceutical manufacturing processes: operation modes and process configurations for monoclonal antibody production"Computer Aided Chemical Engineering, 48, 1609–1614 (2020)

Others

Kozue Okamura "人々の健康に貢献する、社会システムを創りたい。" School of Engineering, The University of Tokyo 【狂ATE the FUTURE】 (2021)

Kozue Okamura, Kensaku Matsunami, Haruku Shirahata, Hirokazu Sugiyama "Conference report: 2019 American Institute of Chemical Engineers Annual Meeting" Pharm Tech Japan, 36, 149–150 (2020)

Kozue Okamura "[学生会員の声] 面白さを開拓することの面白さ" 化学工学, 84(1), 43 (2020)

Awards

Kozue Okamura, "GSDM Student Effort Award AY2020", Global Leader Program for Social Design and Management (GSDM), March 2021

Kozue Okamura, "Dean of the School of Engineering Award", The University of Tokyo, March 2021

Kozue Okamura, "Best presentation award in Department of Chemical System Engineering", The University of Tokyo, March 2021

Kozue Okamura, "Student award", SCEJ 86th Annual Meeting, March 2021

Kozue Okamura, "Student award", SCEJ 84th Annual Meeting, March 2019