Sugiyama Laboratory

2021

Doctor thesis
Anicia Zeberli "Computer-aided approach for design and operation support of changeover processes in biopharmaceutical drug product manufacturing"
Kensaku Matsunami "Integrated design framework for solid drug product manufacturing processes considering continuous technology"

Master thesis
Kozue Okamura "Modeling and design of cell cultivation processes in monoclonal antibody production"
Nozomi Takahashi "Robust design of capture chromatography processes in monoclonal antibody production"
Danny Harjowinoto "Quality and productivity assessment of small-scale tablet manufacturing"

Bachelor thesis
Akinori Shigeyama (Title in Japanese)
Shungo Matsueda (Title in Japanese)
Yuki Yoshiyama (Title in Japanese)

2020

Doctor thesis
Haruku Shirahata "Holistic design of biopharmaceutical production processes considering single-use technology and continuous manufacturing"
Keisho Yabuta "Model-based design of hydrogen peroxide decontamination processes in sterile drug product manufacturing"

Master thesis
Junu Kim "Decision support method for the choice between batch and flow syntheses in drug substance manufacturing"
Kosuke Kusumoto (Title in Japanese)
Tomohiro Miura (Title in Japanese)
Masahiro Yamada "Design method for injectable manufacturing processes considering continuous and batch modes"

Bachelor thesis
Hiroaki Kuroda (Title in Japanese)
Tatsuki Yoshida (Title in Japanese)

2019

Master thesis
Koichi Hayashi (Title in Japanese)
Yusuke Hayashi "Design of freezing processes for human induced pluripotent stem cells towards industrial manufacturing"
Masaki Shiokaramatsu (Title in Japanese)

Bachelor thesis
Kozue Okamura "Dynamic simulation and process assessment of cell cultivation modes in monoclonal antibody production"
Nozomi Takahashi (Title in Japanese)

2018

Doctor thesis
Gioele Casola "Framework for data-driven process improvement and operations support in biopharmaceutical drug product manufacturing"

Master thesis
Shohei Fukuhara (Title in Japanese)
Norikazu Harada (Title in Japanese)
Kensaku Matsunami "Design method of solid drug product manufacturing processes in clinical development"
Philipp Zuercher "Multi-stage and Multi-objective Decision Support Tool for Process Design of Biopharmaceutical Drug Product Manufacturing" (ETH Zurich)

Bachelor thesis
Kosuke Kusumoto (Title in Japanese)
Masahiro Yamada "Lot-sizing method in parenterals manufacturing processes based on economic evaluation" (Original title in Japanese)

2017

Master thesis
Masaaki Ito "Method for material loss reduction in drug product manufacturing processes" (Original title in Japanese)
Haruku Shirahata "Design methodology of parenterals manufacturing processes considering the choice between single-use and multi-use technologies"
Keisho Yabuta "Design methodology of decontamination processes using hydrogen peroxide in pharmaceutical manufacturing"
Shant Dakessian "Systematic generation and evaluation of equipment technology options in parenterals manufacturing" (ETH Zurich)
Anicia Zeberli "Application of computational fluid dynamics for equipment redesign in sterile manufacturing of biopharmaceuticals" (ETH Zurich)

Bachelor thesis
Masaki Shiokaramatsu "Design of working cell bank of allogeneic iPS cells using Monte Carlo simulation" (Original title in Japanese)

2016

Bachelor thesis
Yuuki Uchida "Method for reducing EHS risks of solvent usage of pharmaceutical drug substance manufacturing" (Original title in Japanese)
Akira Hashimoto "Method for supporting countermeasures for reducing unused medicines" (Original title in Japanese)
Kensaku Matsunami "Design method for pharmaceutical tablet manufacturing processes considering the choice between batch and continuous technologies" (Original title in Japanese)

2015

Bachelor thesis
Haruku Shirahata (Title in Japanese)
Akiko Segawa (Title in Japanese)
Keisho Yabuta (Title in Japanese)

2014

Master thesis
Gioele Casola "Systematic retrofitting methodology for pharmaceutical drug purification processes"

Bachelor thesis
Masaaki Ito (Title in Japanese)