Society of Chemical Engineers, Japan (SCEJ) 88th Annual Meeting

15-17 March 2023, University of Agriculture and Technology, Tokyo

1. (PC232) "Decision-support method for pharmaceutical excipients considering supply stability"
   Poster, Kousuke Nemoto, Yusuke Hayashi, Hirokazu Sugiyama Student Award (Poster)
2. (PC229) "Simulation and design of integrated upstream and downstream monoclonal antibody production processes"
   Poster, Akinori Shigeyama, Sara Badr, Yusuke Hayashi, Hirokazu Sugiyama
3. (PC227) "Prediction model of quality and manufacturability based on powder properties for table-top tablet manufacturing"
   Poster, Ayumi Goto, Elena Reus, Yusuke Hayashi, Kazuya Tanabe, Takuya Nagato, Hirokazu Sugiyama Student Award (Poster)
4. (F207) "Hybrid modelling of active pharmaceutical ingredient flow synthesis in ring-opening reaction of an epoxide with a Grignard reagent"
   Oral, Junu Kim, Yusuke Hayashi, Sara Badr, Kazuya Okamoto, Toshikazu Hakogi, Haruo Furukawa, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama
5. (I206) "A comprehensive design approach for injectable manufacturing processes considering new technologies and operational aspects"
   Oral, Masahiro Yamada, Yusuke Hayashi, Sara Badr, Kenichi Zenitani, Kokichi Kubota, Hayao Nakanishi, Hirokazu Sugiyama
6. (I203) "Model-based characterization and evaluation of batch and flow syntheses in drug substance manufacturing"
   Oral, Junu Kim, Hirokazu Sugiyama
7. (I201) "Modeling cell metabolic shifts in cultivation processes for monoclonal antibody production"
   Oral, Kozue Okamura, Sara Badr, Akira Yamada, Hirokazu Sugiyama
8. (D116) [Invited lecture] "The role of data-driven and hybrid modeling in biopharmaceutical manufacturing"
   Oral, Badr Sara
9. (J115) "A CFD model-based design of seeding processes for two-dimensional mesenchymal stem cell cultivation"
   Oral, Benedikt Scholz, Yusuke Hayashi, Isuru Udugama, Masahiro Kino-oka, Hirokazu Sugiyama
10. (I115) "CFD-based investigation of a novel decontamination process using ultrasound technology"
    Oral, Mohamed Rami Gaddem, Yusuke Hayashi, Haruka Futamura, Koji Kawasaki, Hirokazu Sugiyama
11. (J114) "Continuous freezing process design for human induced pluripotent stem cells using CFD simulation"
    Oral, Yusuke Hayashi, Benedikt Scholz, Hirokazu Sugiyama

The 65th Joint Conference on Automatic Control Engineering

12-13 November 2022, Utsunomiya University, Tochigi

1. (2G1-3) "Application of continuous freezing processes for human induced pluripotent stem cells"
   Oral, Yusuke Hayashi, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 53rd Autumn Meeting

14-16 September 2022, Virtual meeting/Shinshu University, Nagano

1. (DC306) "Multi-step approach for data-driven equipment condition assessment in biopharmaceutical drug product manufacturing"
   Oral, Philipp Samuel Zuercher, Sara Badr, Stephanie Knueppel, Hirokazu Sugiyama
2. (DC305) "Data-driven analysis of charge variants in monoclonal antibody production"
   Oral, Yuki Yoshiyama, Sara Badr, Kozue Okamura, Sei Murakami, Hirokazu Sugiyama
3. (BA215) "Application of tunnel freezers in freezing processes for human induced pluripotent stem cells"
   Oral, Yusuke Hayashi, Hirokazu Sugiyama
4. (BA213) "Requirement analysis of therapeutic antibody process simulators"
   Oral, Akira Yamada, Hirokazu Sugiyama
5. (BA208) "Data-driven decision support for equipment condition monitoring and predictive maintenance in biopharmaceutical drug product manufacturing"
   Oral, Philipp Samuel Zuercher, Sara Badr, Stephanie Knueppel, Hirokazu Sugiyama
6. (BA115) "Simulation of monoclonal antibody production processes and application to design"
   Oral, Akinori Shigeyama, Sara Badr, Akira Yamada, Hirokazu Sugiyama
7. (BA114) "Kinetic modelling of nucleophilic aromatic substitution reaction in drug substance synthesis"
   Oral, Junu Kim, Yusuke Hayashi, Sara Badr, Kazuya Okamoto, Toshikazu Hakogi, Haruo Furukawa, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama
8. (AA114) "Modeling approach for cost-effectiveness analysis of companion diagnostics"
   Oral, Kozue Okamura, Seiichi Ohta, Hirokazu Sugiyama

ISPE Japan Affiliate Annual Meeting 2022

19-20 May 2022, Virtual meeting/Tower Hall Funabori, Tokyo

1. (Special lecture 2) "Pharma PSE:医薬品製造を"reimagine"するマルチスケール・アプローチ"
   Oral, Hirokazu Sugiyama

The 21st Congress of the Japanese Society for Regenerative Medicine

17-19 March 2022, Virtual meeting

1. (SY-20-4) "シミュレーションを利用したデザインスペース構築"
   Oral, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 87th Annual Meeting

16-18 March 2022, Tsurukabuto Campus, Kobe University, Kobe city, Hyogo/Virtual meeting

1. (PB268) "Development of a quality prediction model using near infrared spectroscopy in table-top tablet production"
   Poster, Saho Okazaki, Kazuya Tanabe, Takuya Nagato, Hirokazu Sugiyama
2. (PB262) "Scenario analysis of vaccine supply for COVID-19 using mathematical models of infectious diseases"
   Poster, Yusuke Ichida, Kensaku Matsunami, Junu Kim, Kozue Okamura, Sara Badr, Hirokazu Sugiyama
3. (PB259) "A dynamic and probabilistic design space determination method for mesenchymal stem cell cultivation processes"
   Poster, Keita Hirono, Isuru A. Udugama, Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama
4. (M309) "Cost-effectiveness modelling and analysis of companion diagnostics"
   Oral, Kozue Okamura, Rio Hamada, Hiroki Tsuchiya, Seiichi Ohta, Hirokzau Sugiyama
5. (M222) "Inherent digital readiness: The challenges facing data-driven applications in the pharmaceutical industry"
   Oral, Sara Badr, Isuru Udugama, Hirokazu Sugiyama
6. (M214) "Superstructure-based process design for injectable manufacturing"
   Oral, Masahiro Yamada, Isuru A. Udugama, Sara Badr, Kenichi Zenitani, Kokichi Kubota, Hayao Nakanishi, Hirokazu Sugiyama
7. (M213) "Multiscale design of cryopreservation processes for human induced pluripotent stem cells"
   Oral, Yusuke Hayashi, Hirokazu Sugiyama
8. (L219) "Model-based comparison of batch and flow syntheses for heterogeneous hydrogenation reaction in drug substance manufacturing"
   Oral, Junu Kim, Hironori Yonekura, Takeaki Watanabe, Satoshi Yoshikawa, Hayao Nakanishi, Sara Badr, Hirokazu Sugiyama
9. (I204) "Model-based design space determination of mesenchymal stem cell cultivation considering system dynamics and variations"
   Oral, Isuru A. Udugama, Keita Hirono, Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 52nd Autumn Meeting

22-24 September 2021, Tsushima Campus, Okayama University, Okayama city, Okayama/Virtual meeting

1. (LD208) "Fill-freeze-thaw process design of human induced pluripotent stem cells using hybrid models"
   Oral, Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama
2. (LD207) "A systems approach for enhancing the efficiency of downstream purification units for monoclonal antibody production"
   Oral, Sara Badr, Akinori Shigeyama, Nozomi Takahashi, Hirokazu Sugiyama
3. (LD206) "Digital models for generating Big Data Sets: The need, lessons learnt and future perspectives"
   Oral, Isuru Abeykonn Udugama, Christoph Bayer, Murat Kulahci, Krist Gernaey
4. (VE122) "Mathematical models for infectious diseases considering the impacts of mobility, therapeutic agents, and vaccines"
   Oral, Kensaku Matsunami, Junu Kim, Kozue Okamura, Yusuke Ichida, Shungo Matsueda, Sara Badr, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 86th Annual Meeting

20-22 March 2021, Virtual meeting

1. (L217) "Assessment of robustness and operational considerations for the design of integrated mAb manufacturing processes"
   Oral, Sara Badr, Kozue Okamura, Nozomi Takahashi, Hirokazu Sugiyama
2. (L206) "Data-driven anomaly detection, prognostics and diagnostics for operation support in biopharmaceutical manufacturing"
   Oral, Anicia Zeberli, Sara Badr, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
3. (L203) "Data-driven approaches towards equipment health classification using process monitoring information in pharmaceutical manufacturing"
   Oral, Philipp Samuel Zuercher, Sara Badr, Hirokazu Sugiyama
4. (L202) "Cost-effectiveness analysis of allogeneic induced pluripotent cell therapy using agent-based models"
   Oral, Yusuke Hayashi, Kota Oishi, Hirokazu Sugiyama
5. (PA105) "Hybrid modeling of cell cultivation towards integrated design of monoclonal antibody production processes"
   Poster, Kozue Okamura, Sara Badr, Hirokazu Sugiyama Student Award (Poster)
6. (PA102) "Robust design of capture chromatography processes in monoclonal antibody production"
   Poster, Nozomi Takahashi, Sara Badr, Hirokazu Sugiyama

第20回日本再生医療学会総会

2021/3/11-13, オンライン開催

1. (SY-17-1) "細胞製造における Quality by Design の役割と課題"
   口頭, 杉山 弘和
2. (O-02-2) "数値流体力学シミュレーションを用いたヒトiPS細胞緩慢凍結プロセスのスケールアップ検討"
   口頭, 林 勇佑, Scholz Benedikt, 杉山 弘和

The 20th Congress of the Japanese Society for Regenerative Medicine (JSRM)

11-13 March 2021, Virtual meeting

1. (SY-17-1) "Rolls and challenges of Quality by Design in cell manufacturing"
   Oral, Hirokazu Sugiyama
2. (O-02-2) "Computational fluid dynamics simulation-based scale-up of slow freezing processes for human induced pluripotent stem cells"
   Oral, Yusuke Hayashi, Benedikt Scholz, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 51st Autumn Meeting

24–26 September 2020, Online

1. (U307) "Life cycle design of packaging based on environmental and functional Simulation-based optimization of temperature profiles in slow freezing of hiPS cells"
   Oral, Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
2. (W304) "Design method for injectable manufacturing processes considering continuous and batch modes"
   Oral, Masahiro Yamada, Yasuyuki Yoshioka, Hayao Nakanishi, Hirokazu Sugiyama
3. (T217) "Data-driven failure detection and root-cause analysis in changeover processes in biopharmaceutical drug product manufacturing"
   Oral, Anicia Zeberli, Sara Badr, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
4. (T216) "Analysis of the effects of process parameters on start-up operation in continuous wet granulation"
   Oral, Kensaku Matsunami, Ingmar Nopens, Hirokazu Sugiyama, Thomas De Beer
   The Research Encouragement Prize of the Division of SIS
5. (T205) "Holistic design of biopharmaceutical production processes considering single-use technology and continuous manufacturing"
   Oral, Haruku Shirahata, Sara Badr, Hirokazu Sugiyama
6. (C113) [Requested talk] "Systems med&pharma: as a new section in SIS division and a new field"
   Oral, Hirokazu Sugiyama
7. (T101) "Decision support method for the choice between batch and flow syntheses in drug substance manufacturing"
   Junu Kim, Hironori Yonekura, Takeaki Watanabe, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 85th Annual Meeting (Abstract only)

1. (H209) "Scale-up of slow freezing processes for hiPS cells using CFD simulation"
   Yusuke Hayashi, Benedikt Scholz, Hirokazu Sugiyama
2. (H208) "Model-based design of H₂O₂ decontamination processes in sterile drug product manufacturing"
   Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Hirokazu Sugiyama
3. (H207) "Holistic design of biopharmaceutical production processes considering single-use technology and continuous manufacturing"
   Haruku Shirahata, Sara Badr, Hirokazu Sugiyama
4. (H204) "Analysis of the effects of process parameters on start-up operation in continuous wet granulation"
   Kensaku Matsunami, Ingmar Nopens, Hirokazu Sugiyama, Thomas De Beer
5. (PB258) "Process simulation for the decision making on cell cultivation modes in monoclonal antibody production"
   Kozue Okamura, Sara Badr, Hirokazu Sugiyama
6. (M116) "Simulation-based optimization of temperature profiles in slow freezing of hiPS cells"
   Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
7. (PA130) "Decision support method for the choice between batch and flow syntheses in drug substance manufacturing"
   Junu Kim, Hironori Yonekura, Takeaki Watanabe, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama
8. (PA124) "Design method for injectable manufacturing processes considering continuous and batch modes"
   Masahiro Yamada, Yasuyuki Yoshioka, Hayao Nakanishi, Hirokazu Sugiyama

The 19th Congress of the Japanese Society for Regenerative Medicine (JSRM) (Abstract only)

1. (O-40-1) "数理モデルを用いたヒトiPS細胞緩慢凍結プロセスの動的最適化"
   Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama

ISPE Japan Affiliate Annual Meeting 2019

30-31 May 2019, Tower Hall Funabori, Tokyo

1. "Data-driven operation support"
   Oral, Anicia Zeberli
2. "Process design of iPS cell freezing"
   Oral, Yusuke Hayashi
3. "Selection of single-use vs multi-use"
   Oral, Haruku Shirahata
4. "Lot-size determination in injectable manufacturing"
   Oral, Masahiro Yamada
5. "Continuous manufacturing of solid drug products"
   Oral, Kensaku Matsunami
6. "Continuous manufacturing of biopharmaceuticals"
   Oral, Haruku Shirahata
7. "Smart manufacturing and nexus problem of drugs"
   Oral, Hirokazu Sugiyama

The 18th congress of the Japanese society for regenerative medicine

21–23 March 2019, Kobe International Conference Center, Hyogo

1. (PT-01-9, P-01-014) "Design of freeze-thaw processes for induced pluripotent stem cells using physical models"
   Poster, Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Masahiko Hirao, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 84th Annual Meeting

13–15 March 2019, Shibaura Institute of Technology, Tokyo

1. (I203) "Design and assessment of process alternatives for integrated monoclonal antibody production: Opportunities for continuous manufacturing"
   Oral, Sara Badr, Kozue Okamura, Nozomi Takahashi, Haruku Shirahata, Hirokazu Sugiyama
   The Research Encouragement Prize of the Division of SIS
2. (I202) "Online decision-support tool for the equipment technology choice in parenterals manufacturing of biopharmaceuticals"
   Oral, Haruku Shirahata, Yuki Shinno, Shuta Hagimori, Sara Badr, Hirokazu Sugiyama
3. (I201) "Economic evaluation of solid drug product manufacturing processes considering the choice of continuous manufacturing"
   Oral, Kensaku Matsunami, Shuichi Tanabe, Keita Yaginuma, Hirokazu Sugiyama
   Technical Achievement Award of the Division of SIS
4. (G115) "Simulation and assessment of monoclonal antibody production processes considering continuous manufacturing"
   Oral, Hirokazu Sugiyama, Kozue Okamura, Nozomi Takahashi, Haruku Shirahata, Sara Badr
5. (PA113) "Lot-sizing in suspended filling processes of human induced pluripotent stem cells"
   Poster, Masaki Shiokaramatsu, Kazuhiro Fukumori, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
6. (PA110) "Modeling and process assessment of batch and continuous manufacturing in API synthesis"
   Poster, Koichi Hayashi, Sara Badr, Hirokazu Sugiyama
7. (PA107) "Design of freezing processes for human induced pluripotent stemm cells towards industiral manufacturing"
   Poster, Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama
8. (PA104) "Simulation and design of chromatography columns in monoclonal antibody purification"
   Poster, Nozomi Takahashi, Sara Badr, Hirokazu Sugiyama
9. (PA101) "Dynamic simulation and process assessment of cell cultivation modes in monoclonal antibody production"
   Poster, Kozue Okamura, Sara Badr, Hirokazu Sugiyama Student Award (Poster)

Society of Chemical Engineers, Japan (SCEJ) 50th Autumn Meeting

18-20 September 2018, Kagoshima University, Kagoshima

1. (FA306) "Models for supporting the choice between single-use and multi-use technologies in drug product manufacturing of biopharmaceuticals"
   Oral, Hirokazu Sugiyama, Haruku Shirahata, Philipp Zuercher, Sara Badr
2. (EA214) "Data-driven predictive monitoring and operation support for decontamination processes in biopharmaceutical manufacturing"
   Oral, Anicia Zeberli, Sara Badr, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
3. (EA213) "Framework for data-driven process improvement and operations support in biopharmaceutical drug product manufacturing"
   Oral, Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
   Young Investigator Researcher Award of the Division of SIS
4. (EA202) "Freeze-thaw process design of induced pluripotent stem cells using mechanistic models"
   Oral, Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Masahiko Hirao, Hirokazu Sugiyama
5. (EA119) "Process evaluation models for continuous tablet manufacturing based on design of experiments"
   Oral, Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
6. (EA118) "Determination of lot-size in injectable manufacturing by the integrated use of process information"
   Oral, Masahiro Yamada, Sara Badr, Shouko Fukuda, Manabu Nakaya, Yasuyuki Yoshioka, Masahiko Hirao, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 83rd Annual Meeting

13-15 March 2018, Kansai University, Osaka

1. (C306)[Invited lecture] "Decision-support tools for biopharmaceutical manufacturing"
   Oral, Hirokazu Sugiyama
2. (PD373) "Method for reducing EHS risks in drug substance manufacturing considering process characteristics"
   Poster, Shohei Fukuhara, Osamu Nishidate, Shin Kikuchi, Yoshifumi Takahashi, Masahiko Hirao, Hirokazu Sugiyama
3. (H301)[Review lecture] "SDGs and trends in their utilization"
   Oral, Masahiko Hirao
4. (I216) "Development of models for designing decontamination processes in pharmaceutical manufacturing"
   Oral, Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao, Hirokazu Sugiyama
5. (I215) "Process systems engineering research for continuous drug manufacturing"
   Oral, Hirokazu Sugiyama
6. (I214) "Data-driven approaches for process improvement and operation support in biopharmaceutical drug product manufacturing"
   Oral, Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
7. (PB228) "Freeze-thaw process design for industrial manufacturing of induced pluripotent stem cells"
   Poster, Yusuke Hayashi, Masahiro Kino-oka, Ikki Horiguchi, Masahiko Hirao, Hirokazu Sugiyama
8. (PA110) "Methodology for selecting reduction measures of unused medicine considering patient characteristics"
   Poster, Norikazu Harada, Naohisa Yahagi, Masahiko Hirao, Hirokazu Sugiyama
9. (PA103) "Lot-sizing method in parenterals manufacturing processes based on economic evaluation"
   Poster, Masahiro Yamada, Yasuyuki Yoshioka, Manabu Nakaya, Shouko Fukuda, Masahiko Hirao, Hirokazu Sugiyama
10. (PA102) "Design method of solid drug product manufacturing processes in clinical development"
    Poster, Kensaku Matsunami, Masahiko Hirao, Hirokazu Sugiyama Student Award (Poster)
11. (PA101) "Big data-platform for supporting design and operation of biopharmaceutical decontamination processes"
    Poster, Anicia Zeberli, Thomas Roedl, Stephanie Knueppel, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 49th Autumn Meeting

20-22 September 2017, Nagoya University, Aichi

1. (AF220) "Multi-layer and multi-objective design platform for parenterals manufacturing processes"
   Oral, Haruku Shirahata, Shant Dakessian, Masahiko Hirao, Hirokazu Sugiyama
2. (AF218) "Product quality evaluation in batch and continuous manufacturing processes of pharmaceutical tablets"
   Oral, Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
3. (AF119) "Process synthesis in drug product manufacturing integrating equipment technology information"
   Oral, Hirokazu Sugiyama

ISPE Japan Affiliate Annual Meeting 2017 (15th Aniversary Meeting)

18-19 May 2017, Toyama International Conference Center, Toyama

1. "Model 4: Improvement of CIP/SIP processes considering uncertainty"
   Oral, Gioele Casola
2. "Model 3: Decision on the choice of continuous and batch technologies in solid drug product manufacturing"
   Oral, Kensaku Matsunami
3. "Model 2: Design of decontamination processes using hydrogen peroxide"
   Oral, Keisho Yabuta
4. "Model 1: Decision on the choice of single- and multi-use technologies in sterile drug product manufacturing"
   Oral, Haruku Shirahata
5. "Background and objectives of the workshop"
   Oral, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 82nd Annual Meeting

6-8 March 2017, Shibaura Institute of Technology, Tokyo

1. (PE341) "Product quality evaluation of batch and continuous technologies in pharmaceutical tablet manufacturing processes"
   Poster, Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
2. (J220) "Model-based design in the manufacturing of pharmaceuticals and regenerative medicine"
   Oral, Hirokazu Sugiyama
3. (J213) "Process systems engineering research for the realization of the sustainable social system"
   Oral [The SCEJ award for outstanding research achievement], Masahiko Hirao
4. (PA104) "Method for material loss reduction in drug product manufacturing processes"
   Poster, Masaaki Ito, Y. Akimoto, K. Takahashi, Y. Kato, N. Kikuchi, Masahiko Hirao, Hirokazu Sugiyama
5. (PA103) "Application of computational fluid dynamics for equipment redesign in sterile manufacturing of biopharmaceuticals"
   Poster, Anicia Zeberli, Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
6. (PA102) "Design methodology of decontamination processes using hydrogen peroxide in pharmaceutical manufacturing"
   Poster, Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao, Hirokazu Sugiyama
7. (PA101) "Design methodology of parenterals manufacturing processes considering the choice between single-use and multi-use technologies"
   Poster, Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama Student Award (Poster)

The 22nd SCEJ Symposium on Fluidization & Particle Processing

8-9 December 2016, The University of Tokyo, Tokyo

1. "Process systems engineering for pharmaceutical manufacturing"
   Oral, Hirokazu Sugiyama
2. "Biopharmaceutical process optimization: needs and benefits of numerical simulation approaches"
   Poster, Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
3. "Process systems approaches for pharmaceutical tablet manufacturing considering batch and continuous technologies"
   Poster, Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama

Society of Chemical Engineers, Japan (SCEJ) 48th Autumn Meeting

6-8 September 2016, Tokushima University, Tokushima

1. (A309) "The role of integration engineering in bioprocess innovation"
   Oral [Invited lecture], Hirokazu Sugiyama
2. (N221) "Process systems engineering research on pharmaceutical continuous manufacturing"
   Oral, Hirokazu Sugiyama, Kensaku Matsunami
3. (N220) "Process performance assessment based on stochastic simulation in sterile drug product manufacturing"
   Oral, Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama
4. (N219) "Developing process models of hydrogen peroxide decontamination in pharmaceutical manufacturing"
   Oral, Keisho Yabuta, Haruka Futamura, Koji Kawasaki, Masahiko Hirao, Hirokazu Sugiyama
5. (V113) "Risk evaluation models for the design of parenterals manufacturing processes"
   Oral, Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama

ISPE Japan Affiliate Annual Meeting 2016

14-15 April 2016, Tower Hall Funabori, Tokyo

1. "Next steps of Pharma PSE research and expansion as COP"
   Oral, Hirokazu Sugiyama
2. "Analyzing generation of unused medicine and its reduction support method"
   Oral, Akira Hashimoto
3. "Comparative evaluation of single-use and multi-use technologies as a process alternative"
   Oral, Haruku Shirahata

Society of Chemical Engineers, Japan (SCEJ) 81st Annual Meeting

13-15 March 2016, Kansai University, Osaka

1. (M224) "Design problem of pharmaceutical manufacturing processes"
   Oral, Hirokazu Sugiyama
2. (ZAA203) "Designing solvent recovery processes in drug substance manufacturing"
   Poster, Menghe Xu, Mai Matsuura, Yusuke Morikawa, Hirokazu Sugiyama Student Award
   (Poster)
3. (ZAA202) "Design Method for Pharmaceutical Tablet Production Considering Batch &
   Continuous Technologies"
   Poster, Kensaku Matsunami, T. Miyano, H. Arai, H. Nakagawa, Masahiko Hirao, Hirokazu Sugiyama Student Award (Poster)

Society of Chemical Engineers, Japan (SCEJ) 47th Autumn Meeting

9-11 September 2015, Hokkaido University, Hokkaido

1. (N202) "Development of Process Models for Enhancing Yield in Sterile Drug Product Manufacturing"
   Oral, Keisho Yabuta, Masahiko Hirao, Hirokazu Sugiyama
2. (F221) "Process Systems Engineering as a Design Support Tool for Pharmaceutical Production Processes"
   Oral, Hirokazu Sugiyama

ISPE Japan Affiliate Annual Meeting 2015

16-17 April 2015 Tower Hall Funabori, Tokyo

1. "Frontier of engineering research on OPEX"
   Oral, Hirokazu Sugiyama
2. "Process improvement in sterile drug product manufacturing using mathematical models"
   Oral, Keisho Yabuta
3. "Supporting method for the choice between single- and multi-use technologies in manufacturing sterile drug products"
   Oral, Haruku Shirahata

Society of Chemical Engineers, Japan (SCEJ) 80th Annual Meeting

19-21 March 2015, Shibaura Institute of Technology, Tokyo

1. (K323) "Modeling, Simulation and Optimization Research for Pharmaceutical Manufacturing"
   Oral, Hirokazu Sugiyama SIS Division, the SCEJ Young Investigator Researcher Award
2. (YB228) "Method for reducing environmental, health and safety(EHS) risks in pharmaceutical drug substance manufacturing based on multiobjective evaluation"
   Poster, Akiko Segawa, Hirokazu Sugiyama, S. Yoshikawa, T. Toyama, H. Nakanishi, Masahiko Hirao Student Award (Poster)
3. (YB227) "Construction of mathematical model for pharmaceutical batch process"
   Poster, Keisho Yabuta, Hirokazu Sugiyama, Masahiko Hirao
4. (YB224) "Supporting method for the choice between single-and multi-use technologies in manufacturing sterile drug products"
   Poster, Haruku Shirahata, Hirokazu Sugiyama, Masahiko Hirao
5. (YB223) "Multiobjective Design Method for Use Process of Pharmaceutical Ingredients Considering Quality and Cost-Effectiveness"
   Poster, Takayuki Iida, Kosuke Ota, Tomohito Sasozaki, Hirokazu Sugiyama
6. (YB220) "Retrofitting methodology for pharmaceutical drug purification process using simulation technologies"
   Poster, Gioele Casola, Hirokazu Sugiyama, S. Yoshikawa, H. Nakanishi, Masahiko Hirao

Society of Chemical Engineers, Japan (SCEJ) 46th Autumn Meeting

17-19 September 2014 Kyushu University, Fukuoka

1. "Improving Lead Time of Pharmaceutical Production Processes Using Monte-Carlo Simulation"
   Oral, Hirokazu Sugiyama, Lukas Gallus Eberle, Rainer Schmidt

Society of Chemical Engineers, Japan (SCEJ) 79th Annual Meeting

18-20 March 2014 Gifu University, Gifu

1. "Applying Process Systems Engineering in Pharmaceutical Industry: A new Paradigm"
   Oral [Invited Presentation], Hirokazu Sugiyama
2. "Process-based approaches for improving quality and cost-effectiveness in pharmaceutical manufacturing"
   Oral, Hirokazu Sugiyama, Masaaki Ito, Masahiko Hirao
3. "Methods for supporing process improvement in pharmaceutical manufacturing"
   Poster, Masaaki Ito, Hirokazu Sugiyama, Masahiko Hirao

Society of Chemical Engineers, Japan (SCEJ) 45th Autumn Meeting

2013/9/16-18 Okayama University, Okayama

1. "Integration engineering towards better quality and productivity in pharmaceutical production processes"
   Oral [Keynote Lecture], Hirokazu Sugiyama